Opportunity Knocks is a 2008 game show hosted by J.D. Roth, and executive produced by Ashton Kutcher and his Katalyst Productions. It premiered on September 23, 2008 on ABC and Citytv in Canada, but received low ratings, especially in the 18-34 year old age demographic, and was canceled after three episodes. ABC subsequently scheduled the remaining six completed episodes for broadcast on Tuesdays at 8:00 pm beginning on May 26, 2009.

Opportunity Knocks (2008) is currently not available on any services.